JAKJANZ 5MG TABLET by ATCO LABORATORIES contains Tofacitinib 5MG, a prescription Janus kinase (JAK) inhibitor used for selected inflammatory and autoimmune conditions. Tofacitinib works by inhibiting specific JAK-dependent immune signaling pathways, helping reduce excessive inflammation associated with certain chronic diseases.
It may be prescribed for appropriately selected adults with conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Because Tofacitinib affects immune-system activity and has important safety warnings, it should only be used under the supervision of a qualified healthcare professional.
✔️ Helps Control Inflammation – Tofacitinib reduces specific immune signaling pathways involved in chronic inflammatory diseases.
✔️ Rheumatoid Arthritis Management – Used in appropriately selected adults with moderately to severely active rheumatoid arthritis.
✔️ Psoriatic Arthritis Treatment – May help reduce inflammatory activity and improve symptoms associated with active psoriatic arthritis.
✔️ Ulcerative Colitis Management – Used for certain adults with moderately to severely active ulcerative colitis.
✔️ Regulates Immune Signaling – Works through the JAK pathway to reduce excessive cytokine signaling.
✔️ Supports Joint Function – In inflammatory arthritis, controlling inflammation may help improve joint pain, swelling, stiffness, and physical function.
✔️ Convenient Oral Treatment – Available in tablet form for easy oral administration.
✔️ Non-Steroidal Medicine – Tofacitinib is a JAK inhibitor, not a corticosteroid.
Tofacitinib belongs to the Janus kinase inhibitor class, commonly called JAK inhibitors.
JAK enzymes play an important role in transmitting signals from cytokines that regulate immune and inflammatory responses. In autoimmune diseases, excessive signaling from these pathways can contribute to persistent inflammation.
Tofacitinib inhibits JAK activity, particularly JAK1 and JAK3, reducing signaling through several cytokine pathways.
🧬 Inflammatory cytokines
⬇️
⚡ JAK signaling
⬇️
🔥 Excessive immune activity
⬇️
💊 Tofacitinib inhibits JAK signaling
⬇️
📉 Reduced inflammatory signaling
⬇️
🦴 Better control of inflammatory disease
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that primarily affects the joints.
It may cause:
🔹 Joint pain
🔹 Swelling
🔹 Morning stiffness
🔹 Reduced mobility
🔹 Fatigue
🔹 Difficulty with everyday activities
Tofacitinib may be prescribed for appropriately selected adults with moderately to severely active RA when other suitable treatments have not provided adequate benefit or have not been tolerated.
It may help improve:
✔️ Joint symptoms
✔️ Physical function
✔️ Disease activity
✔️ Daily mobility
Psoriatic arthritis is an inflammatory condition associated with psoriasis that can affect the joints, fingers, toes, spine, and other areas.
Possible symptoms include:
🦴 Joint pain
🦵 Joint swelling
🖐️ Finger stiffness
🦶 Toe inflammation
💅 Nail changes
🧍 Back or spinal discomfort
Tofacitinib may be prescribed to appropriately selected adults to help control inflammatory disease activity.
Ulcerative colitis is a chronic inflammatory bowel disease affecting the colon.
Symptoms may include:
🔹 Frequent diarrhea
🔹 Rectal bleeding
🔹 Abdominal discomfort
🔹 Urgency to pass stool
🔹 Colon inflammation
Tofacitinib can be used for certain adults with moderately to severely active ulcerative colitis according to an appropriate physician-directed treatment plan.
🌟 Contains Tofacitinib 5MG – An established JAK inhibitor used for selected inflammatory diseases.
🧬 Targeted JAK Pathway – Modulates specific immune signaling pathways involved in inflammation.
💊 Convenient Tablet Form – Oral administration makes treatment convenient when prescribed.
🏭 ATCO LABORATORIES – JAKJANZ is supplied under the ATCO LABORATORIES brand.
📦 10-Tablet Pack – Convenient pack size for prescribed treatment.
🩺 Requires Medical Monitoring – Appropriate screening and follow-up are important because Tofacitinib affects immune-system function.
⚠️ Take JAKJANZ exactly as prescribed by your doctor.
✔️ Swallow the tablet with water.
✔️ It may generally be taken with or without food.
✔️ Follow the exact dosing schedule provided by your healthcare professional.
✔️ Take doses consistently at the recommended times.
✔️ Do not take more than the prescribed amount.
✔️ Do not stop treatment without consulting your doctor.
✔️ Do not change from 5MG to 10MG or another strength without medical advice.
The correct Tofacitinib dose depends on the condition being treated, treatment phase, kidney function, liver function, age, other medicines, and individual risk factors.
Therefore, JAKJANZ 5MG should only be used according to the prescription provided by your healthcare professional.
Because Tofacitinib modifies immune-system activity, it may increase the risk of serious infections.
These can include:
🔹 Tuberculosis
🔹 Bacterial infections
🔹 Fungal infections
🔹 Viral infections
🔹 Opportunistic infections
Your doctor may screen for tuberculosis and other infections before treatment.
Contact your doctor if you develop persistent fever, cough, unexplained fatigue, or other symptoms of infection.
JAK inhibitors have been associated with an increased risk of certain serious cardiovascular events, particularly among patients with additional risk factors.
Tell your doctor if you have:
❤️ Heart disease
🩸 Previous heart attack
🧠 Previous stroke
🚬 Smoking history
🩺 High blood pressure
🩸 High cholesterol
Your doctor will assess whether Tofacitinib is appropriate for you.
Tofacitinib has been associated with serious blood clots in certain patients.
Seek urgent medical attention if you experience:
🚨 Sudden chest pain
🚨 Difficulty breathing
🚨 Sudden shortness of breath
🚨 Painful swelling in one leg
Tofacitinib may increase the risk of certain malignancies, including lymphoma and other cancers.
Your doctor will consider your individual risk factors and provide appropriate monitoring.
Your doctor may recommend:
🩸 Complete blood count (CBC)
🧪 Liver function tests
🩸 Cholesterol/lipid testing
🦠 Tuberculosis screening
🦠 Other infection screening where appropriate
Regular medical follow-up is important during treatment.
Possible side effects may include:
✔️ Upper respiratory tract infections
✔️ Headache
✔️ Diarrhea
✔️ Increased cholesterol levels
✔️ Increased blood pressure
✔️ Changes in blood counts
✔️ Herpes zoster (shingles)
✔️ Changes in liver enzymes
Serious complications such as severe infections, blood clots, cardiovascular events, or malignancies require prompt medical attention.
🚨 Severe chest pain
🚨 Sudden difficulty breathing
🚨 Sudden weakness or difficulty speaking
🚨 Painful or swollen leg
🚨 Persistent high fever
🚨 Severe infection symptoms
Inform your doctor about all prescription medicines, OTC products, supplements, and herbal medicines you use.
Special caution may be required with:
🔹 Other JAK inhibitors
🔹 Biologic immunosuppressants
🔹 Potent immunosuppressive medicines
🔹 Certain medicines affecting CYP enzymes
Discuss your vaccination status with your doctor before beginning treatment.
⚠️ Live vaccines are generally avoided during Tofacitinib treatment.
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JAKJANZ 5MG TABLET by ATCO LABORATORIES contains Tofacitinib 5MG, a prescription JAK inhibitor used for selected inflammatory and autoimmune conditions including rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
By modifying JAK-dependent cytokine signaling, Tofacitinib helps reduce excessive immune activity and inflammation.
Because this medicine can increase the risk of serious infections and other significant complications, JAKJANZ should only be taken under appropriate medical supervision.
⚠️ Prescription medicine – do not start, stop, or change the dose without consulting your doctor.
✔️ JAKJANZ 5MG contains Tofacitinib, a JAK inhibitor used for selected inflammatory conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.
✔️ No. JAKJANZ contains Tofacitinib, which is a Janus kinase (JAK) inhibitor, not a corticosteroid.
✔️ Tofacitinib may be prescribed to reduce inflammatory disease activity and improve joint symptoms and physical function in appropriately selected adults with rheumatoid arthritis.
✔️ No. Tofacitinib is a prescription medicine requiring medical evaluation and monitoring because it can increase the risk of serious infections and other complications.
📢 JAKJANZ 5MG TABLET by ATCO LABORATORIES is available through SuperCare Pharma, subject to availability and applicable prescription requirements.
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⚠️ Prescription medicine – use only under the supervision of a qualified healthcare professional.
