URISOLIN PLUS 0.4MG/0.5MG Capsule (Tamsulosin HCl + Dutasteride) – Dual-Action Treatment for Enlarged Prostate

URISOLIN PLUS 0.4MG/0.5MG Capsule by Searle Pharma – Helps Improve Urine Flow & Manage Prostate Enlargement

URISOLIN PLUS 0.4MG/0.5MG Capsule by Searle Pharma contains a combination of Tamsulosin Hydrochloride (HCl) 0.4mg and Dutasteride 0.5mg. This prescription medicine combines two complementary approaches for managing benign prostatic hyperplasia (BPH), commonly known as an enlarged prostate.

Tamsulosin helps relax the smooth muscles of the prostate and bladder neck, making it easier for urine to flow. Dutasteride reduces the production of dihydrotestosterone (DHT), a hormone involved in prostate growth, and can gradually help reduce prostate size.

Because the two ingredients work differently, the combination can provide both relatively faster symptom relief and long-term management of prostate enlargement in appropriate patients.

URISOLIN PLUS should be used only according to your doctor's prescription and is generally intended for long-term management when combination therapy is considered appropriate.

What is URISOLIN PLUS 0.4MG/0.5MG Capsule?

URISOLIN PLUS is an oral combination capsule containing:

• Tamsulosin HCl – 0.4mg
• Dutasteride – 0.5mg
• Brand: Searle Pharma
• Dosage Form: Capsule
• Pack Size: 30 Capsules

It is used to manage symptoms associated with benign prostatic hyperplasia (BPH) and may be prescribed to help reduce the risk of BPH progression in appropriate patients.

Common symptoms of an enlarged prostate include:

• Difficulty starting urination
• Weak urine stream
• Interrupted urine flow
• Frequent urination
• Urinary urgency
• Increased nighttime urination
• Feeling that the bladder has not completely emptied
• Dribbling after urination

Key Benefits of URISOLIN PLUS 0.4MG/0.5MG Capsule

✔ Helps Improve Urine Flow

Tamsulosin relaxes smooth muscle around the prostate and bladder neck, reducing resistance to urine flow.

✔ Helps Relieve BPH Symptoms

The combination can help improve troublesome lower urinary tract symptoms associated with an enlarged prostate.

✔ Helps Reduce Prostate Growth

Dutasteride lowers DHT levels, which can gradually reduce prostate volume in men with BPH.

✔ Dual Mechanism of Action

Combines an alpha-1 adrenergic blocker with a 5-alpha-reductase inhibitor.

✔ Supports Long-Term BPH Management

Dutasteride works over time to address the hormonal component of prostate enlargement.

✔ May Reduce the Risk of BPH Progression

In appropriate patients, dutasteride-based treatment can reduce the likelihood of urinary retention and the need for BPH-related surgery.

✔ Convenient Combination Capsule

Two active ingredients are provided in a single dosage form, simplifying the prescribed treatment regimen.

How Does URISOLIN PLUS Work?

URISOLIN PLUS contains two medicines that work through different mechanisms.

Tamsulosin HCl 0.4mg

Tamsulosin selectively blocks alpha-1 adrenergic receptors in the smooth muscle of the prostate and bladder neck.

This causes these muscles to relax, reducing resistance to urine flow.

Prostate/bladder neck relaxation → Lower urinary resistance → Easier urine flow

Tamsulosin can therefore help improve urinary symptoms relatively quickly compared with medicines that reduce prostate size.

Dutasteride 0.5mg

Dutasteride inhibits 5-alpha-reductase, the enzyme responsible for converting testosterone into dihydrotestosterone (DHT).

DHT contributes to prostate growth. By reducing DHT levels, dutasteride can gradually reduce prostate volume and improve urinary symptoms over time.

Together

The combination provides:

Tamsulosin → Relaxes prostate/bladder neck → Helps improve urine flow

Dutasteride → Reduces DHT → Helps reduce prostate size and BPH progression

Medical Uses of URISOLIN PLUS

Your doctor may prescribe URISOLIN PLUS for men with benign prostatic hyperplasia (BPH) who require combination treatment.

It may be used to:

• Improve urinary flow
• Reduce lower urinary tract symptoms
• Help manage an enlarged prostate
• Reduce the risk of acute urinary retention
• Reduce the likelihood of BPH-related surgical intervention in appropriate patients

The medicine does not treat prostate cancer and should not be used as a substitute for appropriate prostate evaluation.

Who May Be Prescribed URISOLIN PLUS?

URISOLIN PLUS may be prescribed for adult men who have:

• Symptomatic benign prostatic hyperplasia
• An enlarged prostate with troublesome urinary symptoms
• Weak or interrupted urine flow
• Difficulty starting urination
• Frequent or urgent urination associated with BPH
• A need for both symptom relief and long-term prostate management

Your doctor will determine whether combination therapy is appropriate based on prostate size, symptoms, medical history, and other factors.

Active Ingredients

Active Ingredient	Strength	Main Function
Tamsulosin HCl	0.4mg	Relaxes smooth muscle in the prostate and bladder neck to improve urine flow
Dutasteride	0.5mg	Reduces DHT production and gradually decreases prostate volume

How to Take URISOLIN PLUS 0.4MG/0.5MG Capsule

• Take URISOLIN PLUS exactly as prescribed by your doctor.
• It is commonly taken once daily.
• Take it at approximately the same time each day if instructed.
• Swallow the capsule whole with water.
• Do not chew, crush, or open the capsule.
• Follow the dosing instructions provided by your doctor and product packaging.
• Continue treatment for as long as recommended.

Because dutasteride works gradually, do not stop treatment simply because symptoms improve.

Important: Do Not Handle Leaking Capsules

Dutasteride can be absorbed through the skin.

Women who are pregnant or may become pregnant should not handle leaking capsules.

If a leaking capsule comes into contact with the skin, wash the affected area immediately with soap and water.

Missed Dose

If you miss a dose, take it when you remember unless it is nearly time for your next scheduled dose.

If it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

Do not take two doses together.

If you have missed several doses, consult your doctor or pharmacist before restarting.

Possible Side Effects

Like all medicines, URISOLIN PLUS may cause side effects.

Common or Possible Side Effects

• Dizziness
• Reduced libido
• Erectile difficulties
• Ejaculation problems
• Breast tenderness or enlargement
• Difficulty maintaining blood pressure when standing
• Weakness
• Headache

Some sexual side effects associated with dutasteride may persist after discontinuation in some patients.

Tamsulosin-Related Effects

Tamsulosin may cause:

• Dizziness
• Light-headedness
• Low blood pressure when standing
• Abnormal ejaculation

Dutasteride-Related Effects

Dutasteride may cause:

• Decreased sexual desire
• Erectile dysfunction
• Ejaculatory problems
• Breast changes

Seek Medical Attention If You Experience

Contact your healthcare professional promptly if you develop:

• Severe dizziness or fainting
• Severe allergic reaction
• Swelling of the face, lips, tongue, or throat
• Difficulty breathing
• Significant breast lumps or nipple discharge
• Prolonged or painful erection
• Serious or unusual symptoms

Warnings & Precautions

Tell your doctor before taking URISOLIN PLUS if you:

• Have low blood pressure
• Have a history of dizziness or fainting
• Have severe liver disease
• Have kidney problems
• Have prostate cancer or are being evaluated for prostate disease
• Are taking medicines for high blood pressure
• Are taking medicines for erectile dysfunction
• Are scheduled for cataract or glaucoma surgery
• Have previously experienced problems with alpha-blocker medicines

Your doctor should know about all prescription medicines, OTC medicines, supplements, and herbal products you use.

URISOLIN PLUS & Prostate Monitoring

BPH symptoms can overlap with other prostate conditions, including prostate cancer.

Dutasteride reduces serum prostate-specific antigen (PSA) levels. Therefore, doctors take dutasteride use into account when interpreting PSA results.

Regular medical follow-up and prostate evaluation may be recommended during long-term treatment.

Do not use changes in urinary symptoms alone to determine whether prostate disease has improved.

URISOLIN PLUS & Dizziness

Tamsulosin can cause dizziness or light-headedness, especially when treatment begins.

To reduce the risk:

• Stand up slowly from sitting or lying down.
• Avoid sudden changes in position.
• Sit or lie down if you feel faint.
• Avoid driving if you feel dizzy.

Seek medical advice if you experience fainting.

URISOLIN PLUS & Cataract Surgery

Tell your ophthalmologist if you are currently taking or have previously taken tamsulosin before cataract or glaucoma surgery.

Tamsulosin has been associated with intraoperative floppy iris syndrome (IFIS) during cataract surgery.

Your eye surgeon should know about current or previous use so appropriate precautions can be taken.

Drug Interactions

Tell your doctor or pharmacist about all medicines you take.

Potentially important interactions include:

• Other alpha-blockers
• Medicines for high blood pressure
• Sildenafil
• Tadalafil
• Vardenafil
• Strong CYP3A4 inhibitors
• Certain antifungal medicines
• Certain antibiotics
• Other medicines that may lower blood pressure

Some medicines can increase tamsulosin or dutasteride exposure or increase the risk of dizziness and low blood pressure.

Do not start or stop medicines without professional medical advice.

URISOLIN PLUS with Sildenafil or Tadalafil

Medicines such as sildenafil and tadalafil can lower blood pressure.

When used with tamsulosin, there may be an increased risk of:

• Dizziness
• Light-headedness
• Low blood pressure
• Fainting

Tell your doctor if you use erectile dysfunction medicines before starting URISOLIN PLUS.

Pregnancy & Breastfeeding

URISOLIN PLUS is intended for use in adult men with BPH.

Women who are pregnant or may become pregnant should not handle leaking capsules, because dutasteride can be absorbed through the skin and may affect the development of a male fetus.

Women should not use this medicine unless specifically directed by a qualified healthcare professional for an appropriate medical reason.

Driving & Machinery

URISOLIN PLUS may cause dizziness or light-headedness.

Avoid driving, riding, or operating machinery until you know how the medicine affects you.

Alcohol Precaution

Alcohol may worsen dizziness or light-headedness in some people taking tamsulosin.

Use caution with alcohol and discuss your alcohol intake with your healthcare provider if you experience dizziness or low blood pressure.

Storage Instructions

• Store URISOLIN PLUS according to the manufacturer's recommended storage conditions.
• Keep capsules in their original packaging.
• Protect from excessive heat and moisture.
• Keep out of reach of children.
• Do not use after the expiry date printed on the package.
• Do not use capsules that are damaged or leaking.

Why Choose URISOLIN PLUS 0.4MG/0.5MG Capsule?

✔ Dual-Action BPH Treatment

Combines Tamsulosin HCl and Dutasteride to address urinary symptoms and prostate enlargement through different mechanisms.

✔ Helps Improve Urine Flow

Tamsulosin relaxes the prostate and bladder neck to reduce urinary resistance.

✔ Supports Long-Term Prostate Management

Dutasteride helps reduce DHT and gradually decrease prostate volume.

✔ Convenient Combination Capsule

Provides both active ingredients in one oral dosage form.

✔ Searle Pharma Product

URISOLIN PLUS is supplied by Searle Pharma.

Customer Reviews

Sample/Placeholder Reviews – for demonstration only

⭐⭐⭐⭐⭐ Ali R. – Lahore

“Sample review: The ordering process was easy, and the medicine arrived securely packed.”

⭐⭐⭐⭐⭐ Usman K. – Karachi

“Sample review: The product was delivered on time and the packaging was in good condition.”

⭐⭐⭐⭐⭐ Hassan M. – Islamabad

“Sample review: Smooth online ordering experience and helpful customer service.”

Product Summary

URISOLIN PLUS 0.4MG/0.5MG Capsule by Searle Pharma contains Tamsulosin HCl 0.4mg + Dutasteride 0.5mg.

It is a prescription combination medicine used for appropriate adult men with benign prostatic hyperplasia (BPH). Tamsulosin relaxes the smooth muscles around the prostate and bladder neck to help improve urine flow, while dutasteride reduces DHT production and gradually helps reduce prostate size.

The combination may provide both symptom relief and long-term management of prostate enlargement when prescribed by a healthcare professional.

Frequently Asked Questions (FAQs)

1. What is URISOLIN PLUS 0.4MG/0.5MG Capsule used for?

URISOLIN PLUS is prescribed for appropriate adult men with benign prostatic hyperplasia (BPH) to help improve urinary symptoms and manage prostate enlargement.

2. What are the ingredients in URISOLIN PLUS?

Each capsule contains Tamsulosin HCl 0.4mg and Dutasteride 0.5mg.

3. Does URISOLIN PLUS shrink the prostate?

Dutasteride can gradually reduce prostate volume by lowering DHT levels, while tamsulosin primarily relaxes the prostate and bladder neck to improve urine flow.

4. Can URISOLIN PLUS cause sexual side effects?

Yes. Dutasteride may cause reduced libido, erectile difficulties, or ejaculation problems in some patients. Tamsulosin may also cause ejaculation changes.

5. Can I take URISOLIN PLUS with sildenafil or tadalafil?

These medicines may increase the risk of low blood pressure and dizziness when used with tamsulosin. Consult your doctor before taking them together.

Why Buy URISOLIN PLUS from SuperCare Pharma?

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We Offer:

✔ Genuine pharmaceutical products

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✔ Dedicated customer support

Prescription medicines should only be used according to the advice of a qualified healthcare professional.

Order URISOLIN PLUS 0.4MG/0.5MG Capsule Online in Pakistan

Looking for URISOLIN PLUS 0.4MG/0.5MG Capsule by Searle Pharma? Order from SuperCare Pharma for a convenient online pharmacy experience and reliable delivery across Pakistan.

Use URISOLIN PLUS exactly as prescribed and maintain regular follow-up with your