TAMU 0.5MG / 0.4MG Capsule by Sanofi-Aventis contains a combination of Dutasteride 0.5mg and Tamsulosin Hydrochloride (HCl) 0.4mg. This dual-action prescription medicine is used to treat moderate to severe symptoms of benign prostatic hyperplasia (BPH), commonly known as an enlarged prostate.
BPH can cause difficulty starting urination, weak urine flow, frequent urination, urgency, nighttime urination, and incomplete bladder emptying. TAMU combines two medicines that work differently: Dutasteride helps reduce prostate enlargement over time, while Tamsulosin relaxes the muscles around the prostate and bladder neck to improve urine flow.
This combination can provide both symptom relief and longer-term management of prostate enlargement when prescribed by a qualified healthcare professional.
TAMU 0.5MG / 0.4MG Capsule contains two active ingredients:
It is a combination medicine belonging to two different drug classes:
The combination is designed to address both prostate enlargement and urinary flow symptoms associated with BPH.
Combines Dutasteride and Tamsulosin to target BPH through two complementary mechanisms.
Dutasteride lowers levels of dihydrotestosterone (DHT), which can gradually reduce prostate volume.
Tamsulosin relaxes smooth muscle around the prostate and bladder neck, helping urine pass more easily.
May help reduce symptoms such as weak urine stream, difficulty starting urination, urgency, frequency, and incomplete bladder emptying.
Dutasteride can help reduce the risk of acute urinary retention and the need for BPH-related surgery in appropriate patients.
Two active ingredients are provided in a single capsule, which can simplify treatment when both medicines are appropriate.
TAMU contains Dutasteride and Tamsulosin, which work in different ways.
Dutasteride inhibits 5-alpha-reductase enzymes, which convert testosterone into dihydrotestosterone (DHT).
DHT contributes to prostate growth. By reducing DHT levels, Dutasteride can gradually decrease prostate size and help improve urinary symptoms over time.
Tamsulosin is an alpha-1 adrenergic receptor blocker. It relaxes smooth muscle in the prostate and bladder neck, reducing resistance to urine flow.
The combination provides:
Dutasteride → reduces prostate size over time
Tamsulosin → relaxes prostate/bladder-neck muscles and improves urine flow
Together, these effects can provide comprehensive management of moderate to severe BPH.
Your healthcare professional may prescribe TAMU for:
The underlying cause of urinary symptoms should be evaluated before treatment.
TAMU may be prescribed for adult men with an enlarged prostate who have:
Not every urinary symptom is caused by BPH. Your doctor may perform examinations and tests to confirm the diagnosis.
| Active Ingredient | Strength | Function |
|---|---|---|
| Dutasteride | 0.5mg | Inhibits 5-alpha-reductase and reduces DHT, helping decrease prostate enlargement |
| Tamsulosin HCl | 0.4mg | Relaxes smooth muscle around the prostate and bladder neck to improve urinary flow |
The capsule contains Dutasteride, which can be absorbed through the skin. Women, children, and adolescents should avoid handling leaking capsules.
If you miss a dose, take it when you remember according to your prescribed schedule.
If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule.
Do not take two capsules together to make up for a missed dose.
If treatment has been interrupted for several days, consult your doctor before restarting.
Tamsulosin may improve urinary symptoms relatively early, while Dutasteride works gradually by reducing DHT and prostate volume.
Do not stop treatment simply because symptoms improve. Long-term treatment may be necessary, and your healthcare professional will determine how long you should continue.
Like all medicines, TAMU 0.5MG / 0.4MG may cause side effects in some patients.
Side effects vary between individuals.
Before taking TAMU, inform your doctor if you:
Dutasteride lowers serum prostate-specific antigen (PSA) levels. Tell your healthcare professional that you are taking Dutasteride before having PSA testing.
Your doctor will interpret PSA results appropriately while you are receiving treatment.
TAMU contains Dutasteride, which can be absorbed through the skin.
Women who are pregnant or may become pregnant should not handle leaking or damaged capsules, because Dutasteride may affect the development of a male fetus.
If a pregnant woman comes into contact with leaking contents, the affected skin should be washed immediately with soap and water.
Keep capsules away from children.
Tamsulosin has been associated with Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery.
If you are taking or have previously taken TAMU, inform your eye surgeon before cataract surgery.
Tamsulosin can lower blood pressure in some patients and may cause:
Be particularly careful when standing up quickly, especially when starting treatment.
TAMU may cause dizziness or light-headedness.
Avoid driving, operating machinery, or performing activities requiring full alertness until you know how the medicine affects you.
Tell your doctor or pharmacist about all medicines you take.
Important interactions may include:
Your doctor may monitor you more closely or adjust treatment when necessary.
Alcohol may increase dizziness or light-headedness caused by Tamsulosin.
Use caution with alcohol, particularly when beginning treatment or if you experience low blood pressure or dizziness.
TAMU is intended for use in adult men and is not indicated for women.
Because the product contains Dutasteride, pregnant women or women who may become pregnant should not handle leaking capsules.
Women who are breastfeeding should not use this medicine unless specifically directed by a healthcare professional for an appropriate medical reason.
Combines Dutasteride 0.5mg + Tamsulosin HCl 0.4mg in one capsule.
Dutasteride targets prostate enlargement while Tamsulosin helps improve urinary flow.
One combination capsule can simplify treatment when both active ingredients are prescribed.
TAMU is supplied under the Sanofi-Aventis brand.
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TAMU 0.5MG / 0.4MG Capsule contains Dutasteride 0.5mg + Tamsulosin HCl 0.4mg, a combination used for the management of moderate to severe symptoms of benign prostatic hyperplasia (BPH).
Dutasteride helps reduce DHT and gradually decreases prostate enlargement, while Tamsulosin relaxes smooth muscle around the prostate and bladder neck to improve urinary flow.
Use TAMU only according to the advice of a qualified healthcare professional.
TAMU contains Dutasteride 0.5mg and Tamsulosin HCl 0.4mg and is used to treat moderate to severe urinary symptoms associated with benign prostatic hyperplasia (BPH).
Dutasteride reduces DHT and gradually helps decrease prostate enlargement, while Tamsulosin relaxes muscles around the prostate and bladder neck to improve urine flow.
Take the capsule exactly as prescribed. It is generally taken once daily and should be swallowed whole. Follow the specific instructions provided by your healthcare professional and product labeling.
Yes. Tamsulosin may cause dizziness or light-headedness, particularly when standing up. Use caution when changing positions and avoid driving if you feel dizzy.
TAMU 0.5MG / 0.4MG Capsule by Sanofi-Aventis may be ordered through SuperCare Pharma, subject to stock availability and applicable prescription requirements.
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If your healthcare professional has prescribed TAMU 0.5MG / 0.4MG Capsule (Dutasteride + Tamsulosin HCl) for BPH symptoms, you can order it from SuperCare Pharma, subject to availability and applicable prescription requirements.
Always use TAMU exactly as directed by your healthcare professional.
