SAFIDE 100MG TABLET
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SAFIDE 100MG TABLET
Product details
Brand: WERRICK PHARMA
Units in Pack: 10
Generic: Safinamide as Mesylate
Appearence / Physical Form: TABLET
SAFIDE 100mg Tablet (Safinamide as Mesylate) 10 Tablets – Advanced Add-On Therapy for Parkinson’s Disease | Werrick Pharma
Regain Better Movement & Reduce "OFF" Time with SAFIDE 100mg Tablet
Living with Parkinson’s disease can become increasingly challenging as symptoms progress over time. While Levodopa remains the gold-standard treatment for Parkinson's disease, many patients eventually experience motor fluctuations, also known as "OFF episodes," where the effects of Levodopa wear off before the next dose. During these periods, symptoms such as tremors, muscle stiffness, slowness of movement, difficulty walking, and impaired balance can return, affecting daily life and independence.
SAFIDE 100mg Tablet, manufactured by Werrick Pharma, contains Safinamide as Mesylate, an innovative selective and reversible Monoamine Oxidase-B (MAO-B) inhibitor that is prescribed as an add-on therapy to Levodopa-containing medicines in adults with Parkinson's disease experiencing motor fluctuations.
Unlike conventional Parkinson's medicines that primarily focus on increasing dopamine levels, Safinamide offers a dual mechanism of action. It not only increases dopamine availability by selectively inhibiting the MAO-B enzyme but also modulates abnormal glutamate release, helping improve motor control in appropriately selected patients. This unique pharmacological profile makes Safinamide a valuable option for neurologists managing patients whose symptoms are no longer adequately controlled with Levodopa alone.
When used under the supervision of a neurologist, SAFIDE 100mg Tablet may help:
- Increase "ON" time (periods when symptoms are well controlled)
- Reduce troublesome "OFF" episodes
- Improve movement and mobility
- Decrease muscle rigidity
- Support smoother motor function
- Enhance overall quality of life
At SuperCare Pharma, we are committed to providing 100% genuine neurological medicines sourced from trusted manufacturers. Order SAFIDE 100mg Tablet online and enjoy secure shopping, competitive prices, and fast nationwide delivery across Pakistan.
What is SAFIDE 100mg Tablet?
SAFIDE 100mg Tablet is a prescription medicine containing Safinamide as Mesylate, a highly selective and reversible Monoamine Oxidase-B (MAO-B) inhibitor indicated as adjunctive therapy with Levodopa/carbidopa (alone or with other Parkinson's medications) for adults with Parkinson's disease who experience end-of-dose motor fluctuations.
Parkinson's disease is a progressive neurodegenerative disorder characterized by the gradual loss of dopamine-producing neurons in the brain. As dopamine levels decline, patients develop symptoms such as tremors, rigidity, slow movements (bradykinesia), impaired balance, and difficulty walking.
Although Levodopa effectively replaces dopamine, many patients develop fluctuations in symptom control after prolonged treatment. SAFIDE helps improve these fluctuations by enhancing dopamine availability and modulating glutamate activity, thereby supporting more consistent symptom control.
How Does SAFIDE 100mg Tablet Work?
Safinamide has a dual mechanism of action, making it different from many traditional Parkinson's medicines.
1. Selective MAO-B Inhibition
Monoamine Oxidase-B (MAO-B) is an enzyme responsible for breaking down dopamine in the brain.
Safinamide selectively and reversibly blocks this enzyme, allowing dopamine produced from Levodopa therapy to remain active for longer periods.
This helps:
- Improve motor function
- Reduce OFF episodes
- Extend ON time
- Enhance Levodopa effectiveness
2. Glutamate Modulation
Safinamide also inhibits excessive glutamate release by acting on voltage-dependent sodium channels.
Abnormal glutamate activity may contribute to motor complications in Parkinson's disease.
By modulating glutamate release, Safinamide may further improve motor stability in selected patients.
Key Benefits of SAFIDE 100mg Tablet
✔ Helps reduce OFF episodes associated with Parkinson's disease
✔ Increases daily ON time when used with Levodopa
✔ Enhances the effectiveness of Levodopa therapy
✔ Improves movement and motor coordination
✔ Helps reduce muscle stiffness (rigidity)
✔ Supports smoother walking and mobility
✔ Improves daily physical functioning
✔ Helps maintain independence in daily activities
✔ Highly selective reversible MAO-B inhibitor
✔ Unique dual mechanism of action
✔ Once-daily oral tablet
✔ Convenient dosing schedule
✔ Clinically established add-on therapy for Parkinson's disease
✔ Manufactured by trusted pharmaceutical company Werrick Pharma
Medical Uses of SAFIDE 100mg Tablet
Doctors may prescribe SAFIDE for:
- Parkinson's disease in adults
- Motor fluctuations ("wearing-off")
- OFF episodes during Levodopa treatment
- Adjunct therapy alongside Levodopa/carbidopa
- Patients requiring improved symptom stability
SAFIDE should only be used under the guidance of a neurologist or qualified healthcare professional.
Symptoms of Parkinson's Disease
Patients who may benefit from SAFIDE often experience:
- Resting tremors
- Muscle stiffness
- Slowed movement (bradykinesia)
- Difficulty walking
- Shuffling gait
- Balance problems
- Freezing episodes
- Reduced arm swing
- Difficulty writing
- Soft speech
- Wearing-off of Levodopa
- Motor fluctuations
Who May Benefit from SAFIDE?
Your neurologist may recommend SAFIDE if you:
- Have Parkinson's disease
- Already take Levodopa
- Experience OFF periods
- Have fluctuating symptom control
- Need improved motor stability
- Require additional Parkinson's symptom management
Who Should Not Use SAFIDE?
SAFIDE may not be suitable for patients who:
- Are allergic to Safinamide or any ingredient
- Have severe liver impairment
- Are taking certain MAO inhibitors
- Have certain retinal disorders
- Have uncontrolled hypertension unless medically evaluated
Always inform your doctor about your complete medical history before starting treatment.
How to Take SAFIDE 100mg Tablet
Always take SAFIDE exactly as prescribed.
General instructions:
- Swallow the tablet whole with water.
- Take once daily or as directed by your physician.
- May be taken with or without food.
- Take it at the same time every day.
- Continue Levodopa and other Parkinson's medicines unless your doctor advises otherwise.
- Do not suddenly stop taking the medicine without medical advice.
Dosage Information
The appropriate dose depends on:
- Current Parkinson's medications
- Disease severity
- Liver function
- Individual response
- Other health conditions
If a dose is missed, take the next scheduled dose at the usual time. Do not double the dose.
Active Ingredient
Safinamide as Mesylate – 100mg
Safinamide is a selective and reversible MAO-B inhibitor that enhances dopamine activity and modulates glutamate release to improve motor function in Parkinson's disease patients receiving Levodopa therapy.
Possible Side Effects
Like all medicines, SAFIDE may cause side effects.
Common Side Effects
- Dyskinesia (involuntary movements)
- Headache
- Nausea
- Insomnia
- Dizziness
- Constipation
- Falls
Less Common Side Effects
- Blurred vision
- Hallucinations
- Anxiety
- Confusion
- Elevated blood pressure
Serious Side Effects
Seek immediate medical attention if you experience:
- Severe allergic reaction
- Chest pain
- Difficulty breathing
- Sudden vision changes
- Severe involuntary movements
- High fever with confusion and muscle stiffness (possible serotonin syndrome in susceptible patients)
Warnings & Precautions
Consult your healthcare provider before taking SAFIDE if you:
- Have liver disease
- Have retinal or eye disorders
- Have uncontrolled hypertension
- Have psychiatric illness
- Are taking antidepressants or serotonergic medicines
- Are pregnant or breastfeeding
- Have kidney disease
Never take SAFIDE without medical supervision.
Drug Interactions
Inform your doctor if you take:
- Levodopa combinations
- Other MAO inhibitors
- SSRIs
- SNRIs
- Tricyclic antidepressants
- Dextromethorphan
- Opioid medicines with serotonergic effects
- St. John's Wort
- Certain decongestants and sympathomimetic drugs
Proper medication review helps minimize the risk of interactions.
Pregnancy & Breastfeeding
There is limited clinical information regarding the use of Safinamide during pregnancy or breastfeeding. It should only be used when the expected benefit outweighs the potential risk, as determined by your healthcare provider.
Storage Instructions
- Store below the temperature stated on the packaging.
- Protect from heat, moisture, and direct sunlight.
- Keep in the original blister pack.
- Keep out of reach of children.
- Do not use after the expiry date.
Why Buy SAFIDE 100mg Tablet from SuperCare Pharma?
✅ 100% Genuine Werrick Pharma Product
✅ Licensed & Trusted Online Pharmacy in Pakistan
✅ Competitive Prices
✅ Fast Nationwide Delivery
✅ Secure Online Payment Options
✅ Carefully Packed Medicines
✅ Responsive Customer Support
✅ Authentic Prescription Medicines
Customer Reviews
⭐⭐⭐⭐⭐ "My neurologist added SAFIDE to my treatment plan, and my OFF periods became less frequent. SuperCare delivered the medicine quickly and in excellent condition." – Imran, Karachi
⭐⭐⭐⭐⭐ "The product was original and well packed. Excellent service and competitive pricing." – Sajid, Lahore
⭐⭐⭐⭐⭐ "After a few weeks of treatment, my daily movement became more consistent alongside my regular Levodopa therapy." – Nadeem, Islamabad
⭐⭐⭐⭐⭐ "Reliable pharmacy with genuine neurological medicines. Highly satisfied with the service." – Bilal, Faisalabad
⭐⭐⭐⭐⭐ "Easy ordering process and fast delivery. Will definitely order again." – Farooq, Multan
Frequently Asked Questions (FAQs)
What is SAFIDE 100mg Tablet used for?
SAFIDE is prescribed as an add-on treatment to Levodopa for adults with Parkinson's disease who experience motor fluctuations or OFF episodes.
What is Safinamide?
Safinamide is a selective and reversible MAO-B inhibitor that increases dopamine availability and also modulates glutamate release to improve motor symptom control.
Is SAFIDE a cure for Parkinson's disease?
No. SAFIDE helps manage symptoms and reduce motor fluctuations but does not cure Parkinson's disease.
Can SAFIDE replace Levodopa?
No. SAFIDE is intended to be used alongside Levodopa, not as a replacement.
How long does SAFIDE take to work?
Some patients may notice improvement within a few weeks, although the response varies depending on individual circumstances.
Can elderly patients take SAFIDE?
Many patients with Parkinson's disease are older adults. Your doctor will determine whether SAFIDE is appropriate based on your health and medications.
Can SAFIDE reduce OFF time?
Yes. Its primary purpose is to reduce OFF episodes and increase ON time when used with Levodopa.
Can I stop taking SAFIDE suddenly?
No. Always consult your doctor before stopping or changing Parkinson's medications.
What are the most common side effects?
Common side effects include dyskinesia, nausea, insomnia, dizziness, headache, and constipation.
Is SAFIDE available in Pakistan?
Yes. Genuine SAFIDE 100mg Tablets are available through SuperCare Pharma, subject to prescription requirements.
Do I need a prescription?
Yes. SAFIDE is a prescription-only medicine.
Can I buy SAFIDE online in Pakistan?
Yes. You can order genuine SAFIDE 100mg Tablet from SuperCare Pharma with nationwide delivery, in accordance with local prescription regulations.
How should I store SAFIDE?
Store it in a cool, dry place in its original packaging, away from heat and moisture.
Who manufactures SAFIDE 100mg Tablet?
SAFIDE 100mg Tablet is manufactured by Werrick Pharma.
Where can I buy original SAFIDE 100mg Tablet in Pakistan?
You can purchase 100% genuine SAFIDE 100mg Tablet from SuperCare Pharma, one of Pakistan's trusted online pharmacies.
Order SAFIDE 100mg Tablet Online from SuperCare Pharma
Support better management of Parkinson's disease with SAFIDE 100mg Tablet (Safinamide as Mesylate). Order today from SuperCare Pharma for genuine medicines, secure online shopping, competitive prices, and fast nationwide delivery across Pakistan.
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