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AVASTIN 100MG/5ML INJECTION

AVASTIN 100MG/5ML INJECTION

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AVASTIN 100MG/5ML INJECTION
Product details
Brand: ROCHE PAKISTAN
Units in Pack: 1
Generic: Bevacizumab
Appearence / Physical Form: INJECTION
Strength / Potency: 100mg

AVASTIN 100MG/5ML INJECTION (Bevacizumab) – Targeted Anti-Cancer Therapy for Advanced & Metastatic Cancers

AVASTIN 100MG/5ML INJECTION contains Bevacizumab, a targeted biological anti-cancer medicine belonging to the class of monoclonal antibodies and anti-angiogenic agents. Avastin works by inhibiting Vascular Endothelial Growth Factor (VEGF), a protein responsible for the formation of new blood vessels that tumors need for growth and spread. By blocking VEGF, Avastin helps slow tumor progression and improve treatment outcomes in several advanced cancers.

Developed by Roche, Avastin is one of the world's most widely used targeted cancer therapies and is prescribed by oncologists as part of combination chemotherapy regimens or targeted treatment protocols. It is indicated for various cancers, including colorectal cancer, lung cancer, ovarian cancer, cervical cancer, kidney cancer, brain tumors, and certain liver cancers.

AVASTIN represents a major advancement in modern oncology because it targets tumor blood supply rather than directly attacking cancer cells, providing a more precise approach to cancer treatment while helping improve progression-free survival in many patients.


Key Benefits of AVASTIN 100MG/5ML INJECTION

✔ Targeted Cancer Therapy – Specifically blocks tumor blood vessel formation.

✔ Helps Slow Cancer Progression – Reduces tumor growth and spread.

✔ Supports Multiple Cancer Treatments – Approved for several advanced malignancies.

✔ Improves Treatment Outcomes – Frequently used in combination with chemotherapy.

✔ Anti-Angiogenic Mechanism – Starves tumors by limiting their blood supply.

✔ Clinically Proven Worldwide – Supported by extensive clinical research and international treatment guidelines.

✔ Personalized Cancer Care Option – Used as part of specialized oncology treatment plans.

✔ Advanced Biologic Therapy – Represents modern targeted cancer treatment.


What is AVASTIN 100MG/5ML INJECTION Used For?

AVASTIN may be prescribed for the treatment of:

Colorectal Cancer

  • Metastatic colorectal cancer
  • Advanced colon cancer
  • Advanced rectal cancer

Lung Cancer

  • Non-squamous non-small cell lung cancer (NSCLC)

Brain Tumors

  • Recurrent glioblastoma

Kidney Cancer

  • Metastatic renal cell carcinoma

Gynecological Cancers

  • Ovarian cancer
  • Fallopian tube cancer
  • Primary peritoneal cancer
  • Cervical cancer

Liver Cancer

  • Hepatocellular carcinoma (in selected treatment regimens)

Treatment decisions depend on the type of cancer, stage of disease, and the patient's overall condition.


How AVASTIN Works

AVASTIN contains Bevacizumab, a recombinant humanized monoclonal antibody that binds to Vascular Endothelial Growth Factor-A (VEGF-A).

By blocking VEGF, Avastin:

  • Prevents new blood vessel formation (angiogenesis)
  • Restricts blood supply to tumors
  • Slows tumor growth
  • Helps reduce cancer spread
  • Enhances the effectiveness of chemotherapy in many cancers

This targeted mechanism allows oncologists to attack a critical pathway required for tumor survival and progression.


Active Ingredient

Bevacizumab

Bevacizumab is a humanized monoclonal antibody and one of the first anti-angiogenic therapies approved for cancer treatment. It has been extensively studied and used globally in oncology practice.


Who Should Receive AVASTIN?

AVASTIN may be prescribed for:

  • Adults with advanced or metastatic cancers
  • Patients undergoing chemotherapy
  • Individuals requiring targeted anti-cancer therapy
  • Patients with recurrent or treatment-resistant malignancies
  • Individuals receiving combination oncology protocols

Treatment should only be administered by qualified oncologists in specialized healthcare facilities.


Dosage & Administration

  • AVASTIN is administered as an intravenous (IV) infusion.
  • The dosage depends on:
    • Body weight
    • Type of cancer
    • Treatment protocol
    • Combination chemotherapy regimen
    • Clinical response

Typical dosing schedules vary from every 2 weeks to every 3 weeks, depending on the cancer being treated. The first infusion is generally administered more slowly and subsequent infusions may be given more rapidly if tolerated.


Important Safety Information

AVASTIN treatment requires careful medical supervision because it may increase the risk of:

  • High blood pressure
  • Bleeding complications
  • Blood clots
  • Delayed wound healing
  • Gastrointestinal perforation
  • Proteinuria (protein in urine)
  • Infusion-related reactions
  • Rare serious cardiovascular complications

Patients receiving Avastin typically undergo regular monitoring throughout treatment.


Possible Side Effects

Some patients may experience:

  • Fatigue
  • Headache
  • High blood pressure
  • Loss of appetite
  • Diarrhea
  • Nosebleeds
  • Protein in urine
  • Weakness
  • Abdominal pain
  • Increased risk of infection

Serious side effects require immediate medical attention and regular monitoring by an oncology specialist.


Precautions & Warnings

Inform your oncologist if you:

  • Are planning surgery
  • Have uncontrolled hypertension
  • Have a history of blood clots
  • Have bleeding disorders
  • Have heart disease
  • Are pregnant or planning pregnancy
  • Are breastfeeding

AVASTIN is generally withheld before and after major surgery because of its effects on wound healing.


Storage Instructions

✔ Store refrigerated at 2°C–8°C.
✔ Do not freeze.
✔ Protect from light.
✔ Do not shake the vial.
✔ Store according to hospital and manufacturer guidelines.


Why Buy AVASTIN from Our Pharmacy?

✅ 100% Genuine Pharmaceutical Products
✅ Proper Cold Chain Storage
✅ Oncology-Specialized Supply
✅ Fast Nationwide Delivery
✅ Secure Ordering Process
✅ Professional Customer Support
✅ Quality-Assured Imported Medicines


Customer Reviews

⭐⭐⭐⭐⭐ "An important part of my father's cancer treatment protocol. Genuine product and excellent service." – Faisal, Karachi

⭐⭐⭐⭐⭐ "Professional handling and proper cold-chain delivery." – Dr. Salman, Lahore

⭐⭐⭐⭐⭐ "Original Avastin supplied exactly as prescribed by our oncologist." – Nida, Islamabad


Frequently Asked Questions (FAQs)

What is AVASTIN 100MG/5ML INJECTION used for?

AVASTIN is used to treat various cancers, including colorectal cancer, lung cancer, ovarian cancer, cervical cancer, kidney cancer, brain tumors, and certain liver cancers.

Is Avastin chemotherapy?

No. Avastin is a targeted biologic therapy (monoclonal antibody) and not a traditional chemotherapy drug.

How does Avastin work?

It blocks VEGF, preventing tumors from developing new blood vessels required for growth and spread.

Can Avastin cure cancer?

Avastin is generally used to help control cancer progression, improve outcomes, and prolong survival as part of comprehensive cancer treatment plans.

Is Avastin a prescription medicine?

Yes. AVASTIN is a specialized prescription oncology medication that must only be administered under the supervision of a qualified oncologist.

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